实用临床医药杂志2019，Vol.23Issue(7)：72-75,4.DOI:10.7619/jcmp.201907019
慢性阻塞性肺疾病合并支气管扩张症患者临床特征及预后相关因素分析
Clinical characteristics of chronic obstructive pulmonary disease patients with bronchiectasis and its related prognostic factors analysis
摘要
Abstract
Objective To explore the clinical characteristics of patients with chronic obstructive pulmonary disease (COPD) complicated with bronchiectasis, and analyze the its prognostic factors. Methods A total of 330 COPD cases in our hospital were divided into group A (simple COPD) and group B (COPD and bronchiectasis) which were divided into survival group and death group according to different prognostic results. The influencing factors of prognosis in COPD patients with bronchiectasis were analyzed by regression analysis. Results There were significant differences in body mass index, history of tuberculosis, duration of symptoms and sputum color between group A and group B (P ＜ 0. 05). The percentage of forced vital capacity to predicted value (FVC％ predicted value), percentage of forced expiratory volume in the first second to predicted value (FEV1％ predicted value), ratio of forced expiratory volume in the first second to forced vital capacity (FEV1/FVC predicted value), partial pressure of blood oxygen [p (O2) ]and albumin level in group A were higher than those in group B (P ＜ 0. 05). The levels of partial pressure of blood carbon dioxide [p (CO2) ], hemoglobin (Hb) and erythrocyte sedimentation rate (ESR) in group A were lower than those in group B (P ＜ 0. 05). There were 33 patients died in group B, with a mortality rate of 22. 76％. Univariate analysis showed that age, duration of symptoms, p (CO2) and albumin were related factors for the prognosis of COPD patients with bronchiectasis, and binary logistic regression analysis showed that age, albumin and duration of symptoms were risk factors for death of COPD patients with bronchiectasis (P ＜ 0. 05 or P ＜ 0. 01). Conclusion The prognosis of COPD patients with bronchiectasis is closely related to age, albuminand duration of symptoms, and albumin level should be monitored.关键词
支气管扩张症/肺疾病/慢性阻塞性/临床特征/预后Key words
bronchiectasis/pulmonary disease/chronic obstruction/clinical features/prognosis分类
医药卫生引用本文复制引用
陈伟,马强,朱镇镇..慢性阻塞性肺疾病合并支气管扩张症患者临床特征及预后相关因素分析[J].实用临床医药杂志,2019,23(7):72-75,4.基金项目
国家自然科学基金资助面上课题(81570072) （81570072）
