摘要
Abstract
Objective To investigate the infection rate, subtypes and distribution characteristics of human papilloma virus (HPV) women in Yangzhou. Methods A retrospective analysis was conducted on 4 682 female patients treated at Northern Jiangsu People's Hospital from May to September 2018. The fluorogenic quantitative PCR was used to detect high-risk HPV typing in cervical exfoliated cells and the results were statistically analyzed. Results A total of 936 positive samples were screened out in 4 682 subjects, the positive rate was 19. 99％, among whom 718 cases with single infection (76. 71％) and 218 with multiple infection (23. 29％) were included. The common subtypes of high-risk HPV infection were HPV 52, 16, 58 and 51, with the positive rate of 25. 00％ (234/936), 20. 73％ (194/936), 16. 67％ (156/936) and 9. 94％ (93/936), respectively. The infection rates of women in different age groups showed significant differences (P ＜ 0. 05), and the higher positive rates distributed in age groups in descending sequence were as follows: 61 ～ 70 years old (32. 00％), 51 ～ 60 years old (26. 32％) and ≤20 years old (21. 43％). Conclusion The main HPV infection is single infection in Yangzhou. Common HPV subtypes are 52, 16, 58, 51, 39, and the patients among age groups have differed HPV subtypes.关键词
人乳头瘤病毒/高危型/宫颈癌/亚型分布Key words
human papilloma virus/high-risk type/cervical cancer/subtype distribution分类
医药卫生
