解放军医学院学报2018，Vol.39Issue(12)：1037-1040,4.DOI:10.3969/j.issn.2095-5227.2018.12.003
2型糖尿病患者校正QT间期与非酒精性脂肪性肝病的相关性分析
Correlation between QT correction interval and non-alcoholic fatty liver disease in type 2 diabetes patients
摘要
Abstract
Objective To determine whether there is a certain correlation between QT correction interval (QTc) and non-alcoholic fatty liver disease in patients with type 2 diabetes.Methods Clinical data about 549 patients with type 2 diabetes in the department of gastroenterology and endocrinology in our hospital from July 2017 to June 2018 were selected for retrospective analysis.QTc interval>440 ms was defined as QTc+.QTc interval≤440 ms was defined as QTc-.Factors that might affect QTc interval, such as gender, heart rate, red blood cells, hemoglobin, etc., were analyzed by logistic regression analysis.Results Male (OR=0.028, 95％CI, 0.116-0.448, P<0.001) and elevated red blood cell (OR=0.231, 95％CI, 0.081-0.662, P=0.006) were independent protective factors of QTc interval prolongation in patients with diabetes.Elevated heart rate (OR=1.040, 95％CI, 1.022-1.058, P<0.001) , obesity (OR=3.350, 95％CI, 1.885-5.951, P<0.001) and NAFLD (OR=1.999, 95％CI, 1.192-3.352, P=0.009) were independent risk factors for the prolongation of QTc interval in patients with diabetes.Conclusion The prolongation of QTc interval in type 2 diabetic patients is closely related to NAFLD confirmed by ultrasonography.关键词
非酒精性脂肪肝病/2型糖尿病/校正QT间期/临床分析Key words
nonalcoholic fatty liver disease/type 2 diabetes/QT correction interval/clinical analysis分类
医药卫生引用本文复制引用
李元枭,汤有才,夏兴洲,殷雪翠,史双伟,张文君,李璇璇,秦珍珍..2型糖尿病患者校正QT间期与非酒精性脂肪性肝病的相关性分析[J].解放军医学院学报,2018,39(12):1037-1040,4.基金项目
国家自然科学基金项目(31471330) （31471330）
河南省科技厅国际合作项目(172102410014) （172102410014）
