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普拉洛芬联合玻璃酸钠治疗老年糖尿病白内障术后干眼症的疗效观察

孙游 赵扬 张玮 吴丽萍 张悦 胡春玲

解放军医学院学报2018,Vol.39Issue(12):1064-1066,3.
解放军医学院学报2018,Vol.39Issue(12):1064-1066,3.DOI:10.3969/j.issn.2095-5227.2018.12.010

普拉洛芬联合玻璃酸钠治疗老年糖尿病白内障术后干眼症的疗效观察

Effect of pranoprofen combined with sodium hyaluronate on xerophthalmia in senile diabetic patients after cataract surgery

孙游 1赵扬 2张玮 1吴丽萍 1张悦 1胡春玲1

作者信息

  • 1. 上海市宝山区仁和医院 眼科,上海 201900
  • 2. 徐州市第三人民医院 眼科,江苏徐州 221000
  • 折叠

摘要

Abstract

Objective To investigate the clinical effect of pranoprofen combined with sodium hyaluronate in treatment of xerophthalmia after diabetic cataract surgery.Methods One hundred and twenty patients with xerophthalmia after cataract surgery in Xuzhou Third People's Hospital from January 2016 to January 2018 were randomly divided into control group and experimental group (with 60 cases in each group) .The control group was treated with sodium hyaluronate (1 drop, 4 times per day) , and the experimental group was treated with pranoprofen (1 drop, 4 times per day) on the basis of sodium hyaluronate treatment.One month later, the clinical effect of the two groups was evaluated using tear film rupture time (BUT) , tear secretion test (SchrmerⅠ) and corneal fluorescent staining score.Results After treatment, BUT and SchrmerⅠin the experimental group were significantly higher than those in the control group[BUT, (11.07±1.66) s vs (7.50±1.02) s;SchrmerⅠ, (7.33±2.11) mm vs (5.03±0.82) mm], while the fluorescence staining score was significantly lower than that in the control group[ (2.13±0.68) vs (4.22±0.67) ] (all P<0.05) .Conclusion Compared with sodium hyaluronate alone, the clinical effect of praprofen combined with sodium hyaluronate in the treatment of xerophthalmia in senile diabetic patients after cataract surgery is more significant.

关键词

普拉洛芬/玻璃酸钠/糖尿病白内障术后/干眼症

Key words

pranoprofen/sodium hyaluronic/after diabetic cataract surgery/xerophthalmia

分类

医药卫生

引用本文复制引用

孙游,赵扬,张玮,吴丽萍,张悦,胡春玲..普拉洛芬联合玻璃酸钠治疗老年糖尿病白内障术后干眼症的疗效观察[J].解放军医学院学报,2018,39(12):1064-1066,3.

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