检验医学与临床2019，Vol.16Issue(3)：306-307,311,3.DOI:10.3969/j.issn.1672-9455.2019.03.006
金标法检测尿β2-MG在肾功能损伤诊断中的临床价值
Clinical value of gold standard method for detecting urinary β2-MG in renal function injury
摘要
Abstract
Objective To evaluate the application value of urinary β2-MG gold standard test kit in the diagnosis of early renal function injury.Methods Fifty-three patients with clinically diagnosed nephrotic syndrome, 40 patients with chronic nephritic syndrome, 18 patients with chronic renal failure, 33 patients with hypertensive nephropathy and 23 patients with diabetic nephropathy served as the study group, and 157 healthy subjects in physical examination as the control group.The urinary β2-MG level was detected by using the β2-MG gold standard test kit and the detection results were compared with those of latex enhanced immunoturbidimetric method.Results There was no statistically significant difference in β2-MG detection results between the gold standard method and latex enhanced immunoturbidimetric method (P>0.05) .The sensitivity of urinary β2-MG detection in 167 patients with clinically confirmed nephropathy was 76.7％, the diagnostic conformity was 85.2％, and the specificity was 94.3％.Conclusion The urinary β2-MG gold standard test kit has a certain clinical application value in the diagnosis of early renal function injury.关键词
β2-微球蛋白/早期肾损伤/金标法Key words
β2-MG/early renal injury/gold standard method分类
医药卫生引用本文复制引用
徐杨,杜惠芬,李克生,李光迪,张瑞君,柴丹丹,连晓雯..金标法检测尿β2-MG在肾功能损伤诊断中的临床价值[J].检验医学与临床,2019,16(3):306-307,311,3.基金项目
甘肃省卫生行业科研计划项目资助(GSWSKY-2015-28). （GSWSKY-2015-28）
