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和肽素对急性心肌梗死早期诊断价值的Meta分析

许斯铤 肖艳 彭溢舒 杨丽君 杨春燕 周琳

检验医学与临床2019,Vol.16Issue(4):456-459,463,5.
检验医学与临床2019,Vol.16Issue(4):456-459,463,5.DOI:10.3969/j.issn.1672-9455.2019.04.007

和肽素对急性心肌梗死早期诊断价值的Meta分析

Meta analysis on early diagnosis value of copeptin in acute myocardial infarction

许斯铤 1肖艳 1彭溢舒 1杨丽君 1杨春燕 1周琳1

作者信息

  • 1. 长沙医学院医学检验系临床生物化学教研室, 长沙 410219
  • 折叠

摘要

Abstract

Objective To evaluate the value of copeptin in the early diagnosis of acute myocardial infarction (AMI).Methods The Meta analysis was adopted.The English databases of PubMed, CNKI, Wanfang, etc.were retrieved.The studies on copeptin in early diagnosis of (AMI) were screened out from their establishment to June 2018.And the analysis was performed by adopting the Meta-disc1.4software.Results A total of10articles were included, involving 6 438study subjects.According to the stochastic effect model, the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and area under the curve (AUC) of copeptin for early diagnosing AMI were 85%, 56%, 2.69, 0.28and 0.917respectively.Conclusion Copeptin is highly sensitive in the early diagnosis of AMI, and can reduce the missed diagnosis rate, but the specificity is slightly poor.

关键词

和肽素/急性心肌梗死/Meta分析

Key words

copeptin/acute myocardial infarction/Meta analysis

分类

医药卫生

引用本文复制引用

许斯铤,肖艳,彭溢舒,杨丽君,杨春燕,周琳..和肽素对急性心肌梗死早期诊断价值的Meta分析[J].检验医学与临床,2019,16(4):456-459,463,5.

基金项目

长沙医学院大学生创新课题(2017078) (2017078)

检验医学与临床

1672-9455

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