林产化学与工业2019，Vol.39Issue(1)：35-40,6.DOI:10.3969/j.issn.0253-2417.2019.01.005
氢化诺卜基二甲基烷基卤化铵的合成及抑菌活性
Synthesis and Antibacterial Activity of Hydronopol Dimethyl Alkyl Ammonium Halide
摘要
Abstract
Nine hydronopol quaternary ammonium salts (hydronopol dimethyl alkyl ammonium halide) , which were hydronopol dimethyl ethyl ammonium bromide (2 a) , hydronopol dimethyl n-propyl ammonium bromide (2 b) , hydronopol dimethyl n-butyl ammonium bromide (2 c) , hydronopol dimethyl n-pentyl ammonium bromide (2 d) , hydronopol dimethyl benzyl ammonium bromide (2 e) , hydronopol dimethyl benzyl ammonium chloride (2 f) , hydronopol dimethyl ethyl ammonium iodide (2 g) , hydronopol dimethyl n-propyl ammonium iodide (2 h) , and hydronopol dimethyl n-butyl ammonium iodide (2 i) , were synthesized by the reaction of hydronopol dimethyl amine and 9 halogenated hydrocarbons, respectively. The identification and structural analysis were carried out by using FT-IR, MS and NMR methods, and the inhibition effects of the nine compounds on eight plant pathogens were tested by the method of mycelium growth rate method. The results showed that under the concentration of 500 mg/L, 9 compounds had certain inhibitory effects on the 8 plant pathogenic fungi, among which the bacteriostatic performance of 2 d were the best, the bacteriostatic rates against Fusarium proliferatum, Alternaria kikuchiana, Sclerotinia sclerotiorum, Ceratosphaeria phyllostachydis, and Sphaeropsis sapinea reached 100％, and 2 b, 2 c and 2 f also had excellent results, the bacteriostatic rate reached 100％.关键词
氢化诺卜基/季铵盐/合成/结构分析/抑菌活性Key words
hydronopol/quaternary ammonium salt/synthesis/structural analysis/bacteriostatic activity分类
化学化工引用本文复制引用
冯雪贞,肖转泉,卢平英,范国荣,王宗德..氢化诺卜基二甲基烷基卤化铵的合成及抑菌活性[J].林产化学与工业,2019,39(1):35-40,6.基金项目
国家自然科学基金项目资助(31660178) （31660178）
江西省主要学科学术和技术带头人培养计划资助(20133BCB22004) （20133BCB22004）
