临床神经外科杂志2019，Vol.16Issue(1)：29-32,37,5.DOI:10.3969/j.issn.1672-7770.2019.01.006
女性颅脑创伤患者的临床因素分析
Clinical factors of female traumatic brain injury
摘要
Abstract
Objective To provide evidence for improving the diagnosis and treatment of female traumatic brain injury (TBI) patients by studying the clinic factors of female TBI patients. Methods The clinical data of 2 368 TBI patients admitted to Department of Neurosurgery, Tianjin Medical University General Hospital from January 2011 to December 2016 were analyzed retrospectively. The clinical features of female patients and the influencing factors of Glasgow Coma Scale (GCS) when they were discharged from hospital were studied. Results The number of female TBI patients was 1/3 of male TBI patients. There were less open-injury and multi-injury patients in female than male TBI patients, but clear increase of the percent of old female TBI patients (≥ 65 years). The primary cause of female TBI patients was traffic accident, while falling was the leading cause of ≥75 years old female TBI patients. There were more female TBI patients upon admission to hospital within 6 hours of injury and less unconscious compared to male patients; but there was no significant difference in the fatality rate between female and male patients (P＞ 0. 05). Univariate analysis showed that age ＜ 65 years, time upon injury to admission≤6 hours, and lower GCS at admission may be the protective factors for GCS improvement of hospitalized women upon discharge (all P ＜0. 05). Multivariate analysis showed that age (OR = 0. 425, 95％ CI: 0. 238-0. 760, P = 0. 004) , time from injury to admission (OR = 0. 576, 95％ CI: 0. 345-0. 962, P = 0. 035) , and GCS on admission (OR = 0. 768, 95％ CI: 0. 713-0. 827, P ＜ 0. 001) influence GCS improvement of TBI women discharged from hospital. Conclusions Injury prevention and reducing the time from injury to admission can improve the therapeutic effectiveness and prognosis of female TBI patients.关键词
颅脑损伤/女 (雌) 性/临床特征Key words
craniocerebral trauma/female/disease attributes分类
医药卫生引用本文复制引用
刘津贤,江荣才,王鹏,高闯,苏万强,黄金浩,钱宇,龚之涛,宋一鸣,孙健..女性颅脑创伤患者的临床因素分析[J].临床神经外科杂志,2019,16(1):29-32,37,5.基金项目
国家自然科学基金 (81671221, 81271359) （81671221, 81271359）
天津市自然科学基金 (14ZCZDSY00179) （14ZCZDSY00179）
