临床眼科杂志2019，Vol.27Issue(1)：16-19,4.DOI:10.399/j.issn.1006-8422.2019.01.005
视网膜静脉阻塞合并黄斑水肿抗VEGF治疗后黄斑中心凹无血管区的变化
The changes in foveal avascular zone area after intravitreal anti-vascular endothelial growth factor injection for macular edema secondary to retinal vein occlusion
李瑾 1张胜娟 2赵伟 3闫配4
作者信息
- 1. 河北省石家庄市第二医院眼科,050000
- 2. 河北省眼科医院 河北省眼科重点实验室 河北省眼科研究所
- 3. 华北石油管理局总医院
- 4. 河北省老年病医院眼科
- 折叠
摘要
Abstract
Objective To evaluate the changes in fovea avascular zone (FAZ) area after the first intravitreal antivascular endothelial growth factor (VEGF) injection for macular edema secondary to retinal vein occlusion (RVO) . Methods In this retrospective case-control studies, 44 eyes with macular edema secondary to RVO was included from April to July2018. They were divided into treatment group (n = 23 cases, 0. 5 mg/0. 05 ml intravitreal injection of Conbercept) and control group (n = 21 cases, not any treatment) . BCVA and OCTA were compared before and after treatment, and central macular thickness (CMT) and superficial retinal capillary network (FAZ) were identified and measured by software. Results The follow-up time was 1 month. BCVA of treatment group patients significantly better than the control group, the difference was statistically significant (P < 0. 05), The CMT of the treatment group was significantly lower than the control group, the difference was statistically significant (P < 0. 05), before and after treatment of shallow retinal capillary network FAZ area change there was no significant difference (P> 0. 05) . Conclusions Single Anti-VEGF treatment of RVO induced macular edema significantly improved the average BCVA and CMT in a short period, and did not aggravate macular ischemia.关键词
抗血管内皮生长因子/黄斑中心凹无血管区/相干光断层扫描血管成像/视网膜静脉阻塞Key words
Anti-VEGF/Foveal avascular zone, Macular edema/Optical coherence tomography angiography/Retinal vein occlusion引用本文复制引用
李瑾,张胜娟,赵伟,闫配..视网膜静脉阻塞合并黄斑水肿抗VEGF治疗后黄斑中心凹无血管区的变化[J].临床眼科杂志,2019,27(1):16-19,4.
