临床与实验病理学杂志2019，Vol.35Issue(3)：295-298,4.DOI:10.13315/j.cnki.cjcep.2019.03.010
梭形细胞/多形性脂肪瘤8例临床病理观察
Spindle cell lipoma/pleomorphic lipoma of soft tissue: a clinicopathologic analysis of 8 cases
展瑞 1赵光明 1郭凌川 2干文娟2
作者信息
- 1. 南通大学附属吴江医院病理科,苏州 215002
- 2. 苏州大学附属第一医院病理科,苏州 215006
- 折叠
摘要
Abstract
Purpose To investigate the clinicopathological features, the diagnosis and differential diagnosis of spindle cell lipoma/pleomorphic lipoma (SCL/PL). Methods Eight cases of SCL/PL were studied by HE staining and immunohistochemistry. The literature was reviewed. Results Microscopically, the neoplasm consisted of spindle cells, mature adipocytes and thick rope-like collagen bundles in variable proportions with mucinous degeneration. The floret-like multinucleated giant cells were easy to be seen in the pleomorphic lipoma. Immunohistochemical analysis revealed that the tumor cells were positive for CD34 and vimentin. The Ki-67 was approximately 2％. The patients were followed up for 3 ～ 74 months, and no recurrence or metastasis occurred. Conclusion The SCL/PL is a special subtype of benign lipoma, surgery is considered the first choice, and outcome is favorable. The diagnosis and differential diagnosis of SCL/PL are important.关键词
脂肪瘤/梭形细胞/多形性/免疫组织化学/鉴别诊断Key words
lipoma/spindle cell/pleomorphic/immunohistochemistry/differential diagnosis分类
医药卫生引用本文复制引用
展瑞,赵光明,郭凌川,干文娟..梭形细胞/多形性脂肪瘤8例临床病理观察[J].临床与实验病理学杂志,2019,35(3):295-298,4.
