山西中医学院学报2018，Vol.19Issue(6)：4-7,16,5.
松龄血脉康胶囊联合钙通道阻滞剂治疗高血压疗效及安全性的Meta分析
Study on efficacy and safety of Songling Xuemaikang capsule combined with CCB in treating hypertension by Meta analysis
摘要
Abstract
Objective:To study efficacy and safety of Songling Xuemaikang capsule combined with CCB in treating hypertension. Methods: All documents which recorded experiments on hypertension patients treated with Songling Xuemaikang capsule and CCB were retrieved by computer from Pubmed, Wanfang database, database and Chinese Biomedical Database, VIP database from setting up to 2014, According to the inclusion and exclusion criteria, a total of 12 documents with 1 621 patients was concluded. The clinical curative effect, the decrease value of systolic blood pressure and diastolic blood pressure, total cholesterol, triglyceride, high density lipoprotein cholesterol were chosen as indices, Meta analysis was performed by RevMan5.3 software.Results: ①The OR of clinical curative effect was 2.49, 95％ CI[1.81, 3.41], P＜0.000 01. It showed that curative effect of treatment group was better than that of control group. ②The decrease values in systolic blood pressure was (WMD=-8.58, 95％ CI[-11.17, -5.99], P=0.000 01).③The decrease value of diastolic blood pressure was (WMD=-6.96, 95％ CI[-9.95, -3.97], P=0.000 01). ④ The total cholesterol was (WMD=-0.67, 95％ CI[-1.08, -0.26], P=0.001) ⑤The triglyceride was (WMD=-0.41, 95％ CI [-0.62, -0.21], P=0.000 1) ⑥The high density lipoprotein cholesterol way (WMD=0.89, 95％ CI [0.33, 1.45], P=0.002). Conclusion: Songling Xuemaikang capsule combined with CCB is effective, security to hypertension.关键词
高血压/松龄血脉康胶囊/钙通道阻滞剂/荟萃分析Key words
hypertension/Songling Xuemaikang capsule/calcium channel blockers/Meta analysis分类
医药卫生引用本文复制引用
丁丽..松龄血脉康胶囊联合钙通道阻滞剂治疗高血压疗效及安全性的Meta分析[J].山西中医学院学报,2018,19(6):4-7,16,5.基金项目
安徽省高校自然科学研究重点项目 (KJ2016A392) （KJ2016A392）
