上海针灸杂志2019，Vol.38Issue(2)：131-136,6.DOI:10.13460/j.issn.1005-0957.2019.02.0131
穴位持续皮下输注胰岛素治疗2型糖尿病疗效观察
Therapeutic Observation of Continuous Subcutaneous Insulin Infusion at Acupoint for Type 2 Diabetes
摘要
Abstract
Objective To observe the difference between continuous subcutaneous insulin infusion (CSII) at acupoint and CSII at non-acupoint in treating type 2 diabetes, for providing a novel option in selecting the insulin injection site. Method Sixty-six subjects with type 2 diabetes were randomized into a treatment group of 32 cases and a control group of 34 cases. The treatment group was intervened by CSII at acupoint, while the control group was intervened by CSII at non-acupoint. The body mass index (BMI), fasting plasma glucose (FPG), 2 h-postprandial plasma glucose (P2hPG), bedtime blood sugar, glycated hemoglobin (HbA1c), consumption of insulin, and the score of diabetes symptom grading and quantification of the two groups were compared. Result The blood sugar level, insulin consumption, HbA1c level and symptom score declined significantly after treatment in both groups (P<0.05);the BMI and initial dosage of insulin in the treatment group dropped significantly after treatment in the treatment group (P<0.05); after treatment, the BMI, FPG level, initial dosage of insulin and symptom score in the treatment group were markedly lower than those in the control group (P<0.05); there were no significant differences between the treatment group and the control group in the P2 hBG level, bedtime glucose sugar level, HbA1c level, pre-prandial insulin dose and total effective rate (P>0.05). Conclusion CSII at acupoint and at non-acupoint both can effectively improve the disease condition of type 2 diabetes. The treatment group is superior to the control group in controlling BMI and FPG, reducing the initial level of insulin, and improving the symptoms, and the treatment group presents a higher total effective rate with the increase of treatment duration compared with the control group. It is indicated that insulin infusion at abdominal acupoint has a certain advantage in the treatment of type 2 diabetes.关键词
糖尿病,非胰岛素依赖/胰岛素泵/穴位疗法/水针Key words
Diabetes, Non-insulin-dependent/Insulin pump/Acupoint therapy/Hydroacupuncture分类
医药卫生引用本文复制引用
刘丽莎,李芹,袁秀丽,段莹,方向明,胥勋梅..穴位持续皮下输注胰岛素治疗2型糖尿病疗效观察[J].上海针灸杂志,2019,38(2):131-136,6.基金项目
四川省中医药管理局中医药科学技术研究专项(2016C068) （2016C068）
