生物加工过程2019,Vol.17Issue(2):117-124,8.DOI:10.3969/j.issn.1672-3678.2019.02.001
L-苯丙氨酸制备的研究进展
Advances in L-phenylalanine preparation
摘要
Abstract
Research progress on chemical and microbial synthesis of L-phenylalanine was reviewed.First,the chemical synthesis routes and enzymatic methods were discussed.Then,advances of the biosynthesis of phenylalanine via microbial fermentation were summarized,and the catalytic mechanisms of Escherichia coli and Corynebacterium glutamicum were also briefly discussed. The applications of L-phenylalanine biosynthesis were emphatically introduced.Finally, future research and applications of L-phenylalanine in biotechnology areas were also discussed.关键词
L-苯丙氨酸/微生物发酵法/重组/大肠杆菌/谷氨酸棒杆菌/代谢机制Key words
L-phenylalanine/microbial fermentation/recombination/Escherichia coli/Corynebacterium glutamicum/catalytic mechanisms分类
生物科学引用本文复制引用
韩建福,富敏霞,祝铃钰,贠军贤..L-苯丙氨酸制备的研究进展[J].生物加工过程,2019,17(2):117-124,8.基金项目
国家自然科学基金(21576240) (21576240)
浙江省自然科学基金(LZ14B060001) (LZ14B060001)