生物加工过程2019，Vol.17Issue(2)：166-170,5.DOI:10.3969/j.issn.1672-3678.2019.02.008
果蝇不同细胞组分转录本多样性
Transcript diversity of different cellular compartments in Drosophila
摘要
Abstract
By using alternative transcription start site, alternative splicing and alternative polyadenylation, eukaryotic genes produce multiple transcript isoforms.The translation efficiency of each transcript is sometimes different, leading to complex relationship between transcript diversity and protein products.We systematically compared the translatome sequencing data of the early embryo of Drosophila with the corresponding transcriptome sequencing data, revealing the difference between the transcript composition of different cellular compartments.Through the analysis of the transcriptome and translatome data, we found 766 genes whose relative transcript isoform abundance changed between different cellular compartments in Drosophila, indicating that different transcripts of many genes in Drosophila may have very different translation efficiency.关键词
转录本异构体/转录组/翻译组/果蝇Key words
transcript isoform/transcriptome/translatome/Drosophila分类
生物科学引用本文复制引用
刘秋芳,李华..果蝇不同细胞组分转录本多样性[J].生物加工过程,2019,17(2):166-170,5.基金项目
国家自然科学基金(31501054) （31501054）
