生物加工过程2019，Vol.17Issue(2)：195-201,7.DOI:10.3969/j.issn.1672-3678.2019.02.013
系统评价中西医结合治疗单纯疱疹病毒性角膜炎的疗效
System evaluation of the efficacy of integrated traditional Chinese and western medicine in the treatment of herpes simplex keratitis
摘要
Abstract
We used wanfang, CNKI and VIP database to amalyze the scientific literatures on integrated traditional Chinese and Western medicine in the treatment of Herpes Simplex Keratitis (HSK) published between 2005 and 2018.Randomized controlled trials (RCT) were collected, quality evaluation was performed and the data were analyzed using Revman 5.3 software.According to the inclusion criteria, the statistical data of methodological quality evaluation, Meta-analysis, funnel map analysis, heterogeneity test and bias risk were carried out through the system Revman 5.3 statistical software.15 RCTs were included, involving 1 521 patients.The results of Meta-analysis showed that the of combination of traditional Chinese and Western medicine group for herpes simplex keratitis had the higher total effective rate[OR=5.23, 95％, CI (3.51, 7.80) , P<0.000 01], the lower recurrence rate[OR=0.32, 95％ CI (0.22, 0.45) , P<0.000 01] and the shorter cure time[MD=-5.40, 95％ CI (-6.41, -4.40) , and P<0.000 01] than that of western medicine alone, the difference was statistically significant.The curative effect of combination of traditional Chinese and Western medicine in treating herpes simplex keratitis is better than that of western medicine alone.It has a good clinical application prospect.关键词
单纯疱疹病毒性角膜炎/中西医结合治疗/系统评价Key words
herpes simplex keratitis/integrated traditional Chinese and western medicine therapy/system evaluation分类
医药卫生引用本文复制引用
王莉,齐梦,李前进,姚杨,雷晓娟,姚巍..系统评价中西医结合治疗单纯疱疹病毒性角膜炎的疗效[J].生物加工过程,2019,17(2):195-201,7.基金项目
西安市科技局医疗卫生研究项目(2017122SF/YX016(5)) （2017122SF/YX016(5）
陕西省社会发展科技攻关项目(2015SF080) （2015SF080）
陕西省重点研发项目-社会发展领域(2017SF-336) （2017SF-336）
