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大豆淫羊藿骨碎补片增加骨密度功能实验研究

禹珊珊 赵倩倩 高洋 高卓林 王莹 金向群

特产研究2019,Vol.41Issue(1):58-61,4.
特产研究2019,Vol.41Issue(1):58-61,4.DOI:10.16720/j.cnki.tcyj.2019.01.012

大豆淫羊藿骨碎补片增加骨密度功能实验研究

Experimental Study on Increased Bone Mineral Density of Soybean Epimedium and Drynaria Tablets

禹珊珊 1赵倩倩 1高洋 1高卓林 1王莹 1金向群1

作者信息

  • 1. 吉林大学药学院,长春 130021
  • 折叠

摘要

Abstract

The effects of soybean epimedium and drynaria tablets on bone mineral density and bone calcium content in rats were investigated.Sixty female Sprague-Dawley rats were randomly divided into 6 groups: sham-operated control group, positive control group, model control group, and low-, medium-, and high-dose groups of soybean epimedium.The above groups of rats were intragastrically administered daily at a dose of 10 mg/kg of rat body for 12 weeks. Rat body weight was weighed and recorded once a week.After 12 weeks, the right femur bone mineral density and bone calcium content of each group of rats were determined.The data showed that the bone mineral density and bone calcium content in the high dose group were significantly higher than the model control group (P < 0.05). It is indicated that the soybean Epimedium sclerotium has the function of increasing bone density in rats.

关键词

大豆淫羊藿骨碎补片/骨密度/骨钙含量

Key words

Soybean epimedium and drynaria tablets/bone density/bone calcium content

分类

医药卫生

引用本文复制引用

禹珊珊,赵倩倩,高洋,高卓林,王莹,金向群..大豆淫羊藿骨碎补片增加骨密度功能实验研究[J].特产研究,2019,41(1):58-61,4.

基金项目

吉林省科技发展计划项目(20170311055YY) (20170311055YY)

特产研究

OACSTPCD

1001-4721

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