武警医学2019，Vol.30Issue(1)：51-53,57,4.
妊娠期血小板减少的病因及结局
Etiology and outcomes of gestational thrombocytopenia
王慧英 1叶艺璇 1于莎莎 1赵棉松2
作者信息
- 1. 首都医科大学附属北京世纪坛医院妇产科, 100038
- 2. 首都医科大学附属北京世纪坛医院风湿免疫科, 100038
- 折叠
摘要
Abstract
Objective To investigate the etiology and outcome of gestational thrombocytopenia. Methods The clinical data on 146 cases of gestational thrombocytopenia treated in Beijing Shijitan Hospital between January 2010 and December 2016 was retrospectively analyzed. These patients were divided into three groups: group Ⅰin which the platelet count was above 50 × 109/L, groupⅡ in which the platelet count was between (30-50) ×109/L, and group Ⅲ whose platelet count was lower than 30 × 109/L. The cause of disease was explored in order to offer targeted treatment. The platelet count of group Ⅰ was monitored closely. Patients vulnerable to bleeding in groups Ⅱ and Ⅲ were treated with glucocorticoid and had their platelet count dynamically monitored. Importance was attached to perinatal surveillance and postpartum visits so as to find out more about the cause of disease. Results The main causes of gestational thrombocytopenia included pregnancy associated thrombocytopenia (PAT), idiopathic thrombocytopenic purpura (ITP) and pregnancy complications. Gestational thrombocytopenia was one of the most important signs of autoimmune diseases. Patients with platelet counts ＜ 30 × 109/L had a significantly higher rate of cesarean section and platelet transfusion than those with platelet counts of (30-50) × 109/L and (50-100) × 109/L (P ＜ 0. 05). Conclusions Clear diagnoses are required in case of gestational thrombocytopenia. Different treatment methods and different ways of delivery should be applied according to etiologies, severity of thrombocytopenia and degree of urgency. Follow-up should last for 3 years after delivery.关键词
妊娠相关性血小板减少症/血小板计数/特发性血小板减少性紫癜Key words
pregnancy associated thrombocytopenia/platelet counts/Idiopathic thrombocytopenic purpura分类
医药卫生引用本文复制引用
王慧英,叶艺璇,于莎莎,赵棉松..妊娠期血小板减少的病因及结局[J].武警医学,2019,30(1):51-53,57,4.
