中国组织工程研究2019，Vol.23Issue(15)：2297-2302,6.DOI:10.3969/j.issn.2095-4344.1165
体外冲击波与膝关节腔内注射透明质酸钠治疗膝骨关节炎的比较
Extracorporeal shock wave therapy versus intra-articular injection of sodium hyaluronate for knee osteoarthritis
刘志成 1宋健 2张其亮3
作者信息
- 1. 青岛市市立医院东院区骨关节与运动医学康复科, 山东省青岛市 266000
- 2. 日照市莒县中医医院骨科, 山东省日照市 276800
- 3. 青岛市市立医院东院区骨关节与运动医学科, 山东省青岛市 266000
- 折叠
摘要
Abstract
BACKGROUND: Intra-articular injection of sodium hyaluronate can safely and effectively treat knee osteoarthritis and obviously improves the pain and function of knee joint. The efficacy of extracorporeal shock wave therapy for early-and middle-term knee osteoarthritis still remains controversial. OBJECTIVE: To compare the effects of extracorporeal shock wave therapy and intra-articular injection of sodium hyaluronate for early-and middle-term knee osteoarthritis. METHODS: According to the inclusion criteria, a total of 77 patients with knee osteoarthritis were enrolled, and randomly divided into extracorporeal shock wave therapy group and sodium hyaluronate therapy group. The extracorporeal shock wave therapy group underwent 5 sessions of 2 000 shockwave pulses performed on the affected knee with the dosage adjusted to 0.2 mJ/mm2 energy. The sodium hyaluronate group was administered intra-articularly sodium hyaluronate once per week for 5 weeks. The results were assessed with the Visual Analogue Scale, Lequesne index and Western Ontario and McMaster Universities Osteoarthritis Index. RESULTS AND CONCLUSION:① After 5 weeks of treatment, the Visual Analogue Scale, Western Ontario and McMaster Universities Osteoarthritis Index and Lequesne index in the two groups were significantly decreased compared with the baseline (P ＜ 0.05). All above indexes in the extracorporeal shock wave therapy group were significantly lower than those in the sodium hyaluronate therapy group (P ＜ 0.05).② These results indicate that the extracorporeal shock wave therapy and sodium hyaluronate therapy are effective for early-and middle-term knee osteoarthritis, and the former is more significant.关键词
膝关节骨性关节炎/体外冲击波/透明质酸钠/关节腔注射/目测类比评分/骨关节炎指数Key words
Knee Joint/Osteoarthritis/Hyaluronic Acid/Tissue Engineering分类
医药卫生引用本文复制引用
刘志成,宋健,张其亮..体外冲击波与膝关节腔内注射透明质酸钠治疗膝骨关节炎的比较[J].中国组织工程研究,2019,23(15):2297-2302,6.
