中风与神经疾病杂志2019，Vol.36Issue(1)：7-9,3.
弥散张量成像测量海马体各向异性分数在帕金森病认知障碍中的应用
Application of hippocampal Fractional Anisotropy in Diagnosis of Parkinson Dementia Disease by Diffusion Tensor Imaging
摘要
Abstract
Objective To observe the changes of hippocampal anisotropy fraction (FA value) by magnetic resonance diffusion tensor imaging (DTI) and evaluate its value as a diagnostic tool for Parkinson's disease (PD) . Methods 12 Parkinson's disease patients (PD group) and 18 matched healthy volunteers (control group) were subjected to magnetic resonance diffusion tensor imaging (DTI) , the DTI parameter anisotropy score (FA value) were analyzed, and the difference of hippocampal FA values between the two groups was compared. Results The left, right and bilateral mean hippocampal FA values of the PD group (0. 168 ± 0. 009、0. 178 ± 0. 009、0. 173 ± 0. 009) were significantly lower than the healthy controls (0. 195 ± 0. 010、0. 207 ± 0. 009、0. 201 ± 0. 009, P < 0. 05) . The FA value of the left hippocampus of the healthy control group PD group was lower than that of the right hippocampus, P < 0. 05. Conclusion The use of hippocampal FA parameters has the prospect of diagnosing Parkinson dementia disease.关键词
帕金森病/各向异性参数/弥散张量成像/海马体Key words
Diffusion tensor imaging/Parkinson disease/Hippocampal分类
医药卫生引用本文复制引用
陈旭辉,林志坚,吴军,叶辰飞,郑晓东..弥散张量成像测量海马体各向异性分数在帕金森病认知障碍中的应用[J].中风与神经疾病杂志,2019,36(1):7-9,3.基金项目
深圳市科技科技创新委员会:知识创新计划基础研究项目:《多系统萎缩的3.0T磁共振弥散张量成像研究》立项课题编号:(No.JCYJ201304021147021) （No.JCYJ201304021147021）
