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肺低级别神经内分泌肿瘤的系统治疗

王峥 程世钊 周方 韩兴鹏 卢喜科 孙大强 张逊

中国肺癌杂志2019,Vol.22Issue(1):34-39,6.
中国肺癌杂志2019,Vol.22Issue(1):34-39,6.DOI:10.3779/j.issn.1009-3419.2019.01.07

肺低级别神经内分泌肿瘤的系统治疗

Systemic Therapy for Low-grade Pulmonary Neuroendocrine Tumor

王峥 1程世钊 1周方 1韩兴鹏 1卢喜科 1孙大强 1张逊1

作者信息

  • 1. 天津市胸科医院胸外科 300000 天津
  • 折叠

摘要

Abstract

The lung is the second most common site of neuroendocrine tumors (NETs).Typical and atypical carcinoids are low-grade NETs of the lung.These rare tumors have received little attention and education is needed for treating physicians.The article describes the classifcation of lung NETs, the epidemiology and pathological characteristics.When lung NETs are diagnosed at an early stage, surgical intervention is often curative.For advanced lung NETs patients, different treatment methods including chemotherapy, somatostatin analogs, m-TOR inhibition, peptide receptor radioligand therapy, and biologic systemic therapy are discussed.The conclusions are generally extrapolated from the outcome of extra-pulmonary carcinoids.Prospective randomized well-designed trials are urgently needed to inform current recommendations on systemic treatment.

关键词

神经内分泌肿瘤//治疗

Key words

Neuroendocrine tumor/Lung/Therapy

引用本文复制引用

王峥,程世钊,周方,韩兴鹏,卢喜科,孙大强,张逊..肺低级别神经内分泌肿瘤的系统治疗[J].中国肺癌杂志,2019,22(1):34-39,6.

中国肺癌杂志

OA北大核心CSCDCSTPCDMEDLINE

1009-3419

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