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PD-L1检测方法在非小细胞肺癌的研究进展

郭雪晶 曹赫 周建娅 周建英

中国肺癌杂志2019,Vol.22Issue(1):40-44,5.
中国肺癌杂志2019,Vol.22Issue(1):40-44,5.DOI:10.3779/j.issn.1009-3419.2019.01.08

PD-L1检测方法在非小细胞肺癌的研究进展

Progress on the Study of PD-L1 Detection Methods in Non-small Cell Lung Cancer

郭雪晶 1曹赫 1周建娅 1周建英1

作者信息

  • 1. 浙江大学医学院附属第一医院呼吸内科 310000 杭州
  • 折叠

摘要

Abstract

PD-1/PD-L1 inhibitors play an important role in the first-line and second-line treatment of non-small cell lung cancer (NSCLC), indicating a new treatment strategy of NSCLC.Completed clinical trials have shown that effective detection of PD-L1 expression is the key to the use of immunosuppressive agents.However, the gold standard for PD-L1 detection has still lacked.In recent years, immunohistochemistry (IHC) and enzyme-linked immunosorbent assay (ELISA) have been continuously innovated, which accounts for good prospect in PD-L1 detection.The research progress of PD-L1 detection methods in NSCLC is summarized in this review.

关键词

PD-L1/非小细胞肺癌/免疫组织化学技术/酶联免疫吸附测定

Key words

PD-L1/Non-small cell lung cancer/Immunohistochemistry/Enzyme-linked immunosorbent assay

引用本文复制引用

郭雪晶,曹赫,周建娅,周建英..PD-L1检测方法在非小细胞肺癌的研究进展[J].中国肺癌杂志,2019,22(1):40-44,5.

基金项目

国家自然科学基金项目(No.81672299)资助 (No.81672299)

中国肺癌杂志

OA北大核心CSCDCSTPCDMEDLINE

1009-3419

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