中国感染控制杂志2019，Vol.18Issue(2)：111-114,4.DOI:10.12138/j.issn.1671-9638.20193894
消化ICU耐碳青霉烯类肺炎克雷伯菌感染暴发调查与控制
Investigation and control of infection outbreak of carbapenem-resistant Klebsiella pneumoniae in a gastroenterology intensive care unit
摘要
Abstract
Objective To investigate and control the outbreak of infection caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) in a gastroenterology intensive care unit (ICU), so as to provide reference for the prevention and control of clinical multidrug-resistant organisms (MDROs).Methods Epidemiological investigation was conducted on 3 patients with CRKP infection in a gastroenterology ICU on January 21-31, 2018, specimens were collected with environmental biology monitoring method, CRKP in environment was searched, homology between patients and environmental isolates were analyzed by pulsed-field gel electrophoresis (PFGE).Results Three patients were all isolated CRKP from sputum and blood specimens, all were male, with adjacent beds in the same ward, and treated by the same doctor.The number of isolated CRKP and infection rate in January 2018 were higher than those in other months, infection rate was significantly different (χ2=13.67, P＜0.01).A total of 102 environmental specimens were collected, including air and surface of objects, only 1 of which (nurse's uniform) was isolated 1 strain of KP.PFGE typing of KP isolated from patients and environment showed that there were two genotypes A and B, KP isolated from uniform of a nurse, hydrops abdominis and blood specimen of patient at bed 07, blood specimen of patient at bed 08, as well as sputum and blood specimen of patient at bed 09 were all type A, KP isolated from sputum specimen of patient at bed 07 was type B, KP isolated from hydrops abdominis in patient at bed 09 was not be typed.After comprehensive intervention, CRKP was not no longer isolated from 3 patients, and there was no new case in the ward.Conclusion Imperfect implementation of prevention and control measures for MDROs by health care workers may be an important cause for the spread of CRKP.关键词
耐碳青霉烯类肺炎克雷伯菌/医院感染/暴发/调查/控制Key words
carbapenem-resistant Klebsiella pneumoniae/healthcare-associated infection/outbreak/investigation/control分类
医药卫生引用本文复制引用
廖睿纯,邓琼,何思云,余奇,徐珍,周芸,曹先伟,庞水子..消化ICU耐碳青霉烯类肺炎克雷伯菌感染暴发调查与控制[J].中国感染控制杂志,2019,18(2):111-114,4.基金项目
江西省科技厅重点项目(20152ACG70015) （20152ACG70015）
