中国临床药理学杂志2019，Vol.35Issue(7)：703-705,3.DOI:10.13699/j.cnki.1001-6821.2019.07.030
同种异体肝移植术后真菌感染的病原菌特点及其相关危险因素分析
Pathogenic characteristics and related risk factors of fungal infection after allograft liver transplantation
马军 1吕少诚 1寇建涛 1李先亮 1朱继巧 1贺强 1李鹏飞2
作者信息
- 1. 首都医科大学 附属北京朝阳医院 肝胆外科,北京 100020
- 2. 首都医科大学 附属北京朝阳医院 药事部,北京 100020
- 折叠
摘要
Abstract
Objective To investigate the clinical characteristics and related risk factors of early fungal infection in the patients after allograft liver transplantation. Methods We have retrospectively analyzed the clinical data of 19 patients with fungal infection in perioperative stage of liver allograft transplantation, analyzed pathogenic characteristics and related risk factors of fungal infection in patients. Results In our research, perioperative fungal infection rate of allograft liver transplantation was 6. 4％ (19 cases/298 cases) . All of fungal infection patients were single fungal infection, including 4 cases of pulmonary fungal infection and 15 cases of abdominal fungal infection. The most common pathogenic bacterias of fungal infection were Candida albicans, Candida tropicalis and Candida glabrata. Multivariate analysis showed that model of end-stage liver disease (MELD) score and acute rejection were independent risk factors of fungal infection (all P < 0. 05) . Conclusion Fungal infection is a common complication after allograft liver transplantation. MELD score and acute rejection may be the independent risk factors of fungal infection.关键词
肝移植/真菌感染/危险因素/治疗Key words
liver transplantation/fungal infection/risk factor/treatment分类
医药卫生引用本文复制引用
马军,吕少诚,寇建涛,李先亮,朱继巧,贺强,李鹏飞..同种异体肝移植术后真菌感染的病原菌特点及其相关危险因素分析[J].中国临床药理学杂志,2019,35(7):703-705,3.
