经内镜黏膜下剥离术治疗62例直肠神经内分泌肿瘤不完整切除危险因素分析OACSCDCSTPCD

Objective To analyze the risk factors for incomplete endoscopic submucosal resection of rectal neuroendocrine neoplasms (r-NENs) and offer clinical experience after incomplete endoscopic submucosal resection. Methods From February 2012 to February2018, 62 cases of rectal carcinoid tumors resected by endoscopic submucosal dissection (ESD) were enrolled, and the factors associated with incomplete endoscopic resection were retrospectively analyzed by univariate and multivariate analysis. Results Univariate analysis demonstrated that depth of infiltration (P<0.05) and central depression of the surface mucosa (P<0.05) were risk factors for incomplete resection of ESD in rectal neuroendocrine neoplasms. Multivariate analysis revealed that central depression of the surface mucosa (P= 0.031) and infiltration of the lesion into the submucosa (P= 0.014) were independent risk factors for incomplete resection of rectal neuroendocrine neoplasms. Conclusion Depth of infiltration into submucosa and the central depression of surface are associated with incomplete resection of rectal neuroendocrine neoplasm. After an incomplete ESD resection of rectal neuroendocrine neoplasm, without evidence of lympho-vascular invasion, a periodic follow-up examination may be considered.