中国体外循环杂志2019，Vol.17Issue(1)：8-12,5.DOI:10.13498/j.cnki.chin.j.ecc.2019.01.03
成人患者术前终末期肝病模型衍生积分与心脏术后体外膜肺氧合辅助急性肾功能损伤的关系
Association of preoperative MELD-XI score with acute kidney injury in adult patients after cardiac surgery treated with veno-arterial extracorporeal membrane oxygenation
摘要
Abstract
Objective To retrospect the outcomes of postoperative adult patients in our center and to explore whether there was a correlation between the preoperative MELD-XI score and acute kidney injury (AKI) in adult patients treated with extracorporeal membrane oxygenation (ECMO) so as to determine the risk factors of AKI and the prognosis of those patients. Methods We reviewed181 cases of postoperative patients treated with ECMO from 2012 to 2015 in our center. The preoperative MELD-XI score and the morbidity of AKI after 24 h and 48 h of ECMO running were calculated to explore the possible association. Results There were statistical differences in baseline MELD-XI score, pre-ECMO serum lactic acid level, serum creatinine and urea nitrogen at 24 h and 48 h of ECMO running, RRT treatment and mortality between patients with AKI and patients without AKI, P ＜ 0.05. High MELD-XI score was a predictor of AKI after 48 h of ECMO running. Conclusion Preoperative baseline MELD-XI score can be used to predict the risk of AKI for postoperative patients treated with VA-ECMO. We can calculate the baseline MELD-XI score to evaluate their risk of AKI.关键词
体外膜肺氧合/急性肾损伤/MELD-XI评分/危险因素/心脏外科/成人Key words
Extracorporeal membrane oxygenation/Acute kidney injury/MELD-XI/Risk factor/Cardiac surgery/Adult引用本文复制引用
丁晓晨,谢海秀,杨峰,侯晓彤..成人患者术前终末期肝病模型衍生积分与心脏术后体外膜肺氧合辅助急性肾功能损伤的关系[J].中国体外循环杂志,2019,17(1):8-12,5.基金项目
国家重点研发计划 (2016YFC1301001) （2016YFC1301001）
首都临床特色应用研究与成果推广 (Z161100000516017) （Z161100000516017）
