摘要
Abstract
Objective To investigate the clinical efficacy and safety of coronary artery bypass grafting (CABG) on the beating heart with cardiopulmonary bypass (CPB) in the treatment of severe coronary artery disease. Methods From January 2014 to October2017, 50 patients with severe coronary heart disease underwent traditional CPB coronary artery bypass grafting or CPB coronary artery bypass grafting on the beating heart were retrospectively studied. The number of graft vessels, CPB time, mechanical ventilation time, the ICU stay, the hospitalization time, cardiac troponin levels, cardiac function indexs, complication incidence and the mortality were compared between the two groups. Results The number of graft vessels in the beating group was less than that in the arrest group (P＜ 0.05). CPB time, mechanical ventilation time and the duration of ICU stay were shorter than those in the arrest group (P ＜0.05).After the treatment, the levels of c Tn I and c Tn T in the two groups were significantly lower than those before the treatment (P ＜0.05).However, the c Tn I and c Tn T in the beating group were lower than those in the arrest group (P ＜0.05). The 6-minute walking distance and the left ventricular ejection fraction (LVEF) in both groups were significantly higher than those before the treatment (P ＜0.05), while the N-terminal brain natriuretic peptide precursor (NT-pro BNP) significantly decreased after the treatment (P ＜0.05). The 6-minute walking distance and the left ventricular ejection fraction in the beating group was higher than those in the arrest group (P ＜0.05), while its NT-pro BNP was lower (P ＜0.05). The incidence of complications in the beating group was lower than that in the arrest group (P ＜0.05), and the mortality was also lower (P ＜ 0. 05). Conclusion Cardiopulmonary bypass coronary artery bypass grafting on the beating heart can effectively improve the heart function, promote the recovery, reduce complications and improve the prognosis of severe coronary artery disease.关键词
冠状动脉粥样硬化性心脏病/体外循环/心脏不停跳/冠状动脉旁路移植术/心功能/重症Key words
Coronary artery disease/Cardiopulmonary bypass/Heart beating/Coronary artery bypass grafting/Heart function/Critical illness
