中国现代手术学杂志2019，Vol.23Issue(1)：21-25,5.DOI:10.16260/j.cnki.1009-2188.2019.01.005
基于倾向性评分法探讨胆道腔内射频消融联合支架置入术治疗恶性胆道梗阻的临床疗效
A Propensity Score Matching of Percutaneous Intraluminal Radiofrequency Ablation Combined with Stent Implantation for Malignant Biliary Obstruction Patients
代鸿华 1张绍平 1杨慧林 1王智 1阎雄2
作者信息
- 1. 重庆医科大学附属第一医院綦江医院(重庆市綦江区人民医院肝胆外科), 重庆 401420
- 2. 重庆医科大学附属第一医院肝胆外科, 重庆 400010
- 折叠
摘要
Abstract
Objective To explore the clinical efficacy of percutaneous intraluminal radiofrequency ablation combined with stent implantation for malignant biliary obstruction patients. Methods The clinical data of 63 cases with malignant biliary obstruction from January 2013 to January 2016 were enrolled. Among them, 24 patients underwent percutaneous intraluminal radiofrequency ablation combined with stent implantation (radiofrequency group) and 39 patients underwent biliary stent implantation alone (stent group). The propensity score matching was conducted to reduce confounding bias. The changes of bilirubin and follow-up results between the two groups were compared after matching. Results There were 19 pairs generated after propensity score matching. The level of total bilirubin (TBil) and direct bilirubin (DBil) on 7-and 14-day postoperatively in the two groups were significantly lower than the preoperative ones (P＜0.05). But the differences of the level of TBil and DBil on 7- and 14-day postoperatively and incidence of postoperative complications was not statistical (P＞ 0.05). In the radiofrequency group, the 3-, 6-, 12-month patency and survival rate were higher than that of the stent group, but only the difference in the 6-month patency rate between the two groups was statistical (P＜0. 05). Meanwhile, the overall survival time in the radiofrequency group was significantly higher than that in the stent group (P＜ 0.05). Conclusions Percutaneous intraluminal radiofrequency ablation combined with stent implantation for malignant biliary obstruction is safe and effective. Comparing with stent implantation alone, it can slow the progression of biliary tract restenosis and prolong the survival time.关键词
恶性胆道梗阻/射频消融/胆道支架/倾向性评分匹配法Key words
malignant biliary obstruction/radiofrequency ablation/biliary stents/propensity score matching分类
医药卫生引用本文复制引用
代鸿华,张绍平,杨慧林,王智,阎雄..基于倾向性评分法探讨胆道腔内射频消融联合支架置入术治疗恶性胆道梗阻的临床疗效[J].中国现代手术学杂志,2019,23(1):21-25,5.
