中国畜牧兽医2019，Vol.46Issue(1)：72-79,8.DOI:10.16431/j.cnki.1671-7236.2019.01.009
动物黑色素细胞及其相关性状形成机制的研究进展
Research Advances on the Formation Mechanism of Animal Melanocytes and Its Related Traits
摘要
Abstract
Melanocytes are melanin-producing cells that are differentiated from their precursor melanoblasts.Melanoblasts are formed in two migration pathways in embryonic stage.The first is dorsolateral pathway which neural crests take when they are specified as melanoblasts, the second is ventral pathway where Schwann cell precursors (SCPs) , a sub-cellular neural stem cell, are formed, and induced to differentiate into melanoblasts, and melanoblasts from SCP are the major source melanocytes in the skin.The formation of melanocytes is closely related to animal hair color and other important economic traits, and the increase or decrease of melanocyte formation, ectopic formation or ectopic invasion may lead to the corresponding disease, but Silky fowl, a vertebrate which has typical ectopic melanocytes is healthy, and is an economic breed for food and me-dicinal usage.Exploring the formation mechanism of melanocytes and its influencing factors, as well as the ectopic formation of melanocytes not only provides informative theoretical basis for the breeding of animal economic traits but also provides a very important theoretical basis for the treatment of related diseases.This paper would explore the cell origin of melanocyte and the factors affecting the melanocytes formation from different origin, and discuss the formation mechanism of melanocyte-related traits, especially the black characteristics of Silky fowl.关键词
黑色素细胞/形成/雪旺氏细胞前体(SCPs)/异位形成Key words
melanocytes/formation/Schwann cell precursors (SCPs) /ectopic formation分类
农业科技引用本文复制引用
熊和丽,席冬梅,李国治,王利平,刘相莹,苑梦雅,李静,邓卫东..动物黑色素细胞及其相关性状形成机制的研究进展[J].中国畜牧兽医,2019,46(1):72-79,8.基金项目
云南省自然科学基金(2016FA007) （2016FA007）
国家自然科学基金(31660634) （31660634）
国家重点研发计划项目(2018YFD0502000) （2018YFD0502000）
