中国医科大学学报2019，Vol.48Issue(1)：48-52,5.DOI:10.12007/j.issn.0258-4646.2019.01.010
腹腔镜下广泛性子宫切除术治疗子宫颈鳞状细胞癌的临床疗效
Clinical Effect of Laparoscopic Radical Hysterectomy on Cervical Squamous Cell Carcinoma
摘要
Abstract
Objective To evaluate the clinical efficacy of laparoscopic radical hysterectomy and pelvic lymph node dissection (PLND) in cervical squamous cell carcinoma (CSCC). Methods The clinical data of 83 CSCC patients in our hospital were retrospectively analyzed. The open surgery group (n = 43) underwent traditional transabdominal radical hysterectomy and PLND, while the laparoscopy group (n = 40) underwent laparoscopic radical hysterectomy and PLND. Intraoperative and postoperative indices were compared between the two groups. Results The intraoperative bleeding volume in stage ⅠB1 and ⅡAl patients in the open surgery group was greater than in the laparoscopy group. The operative duration was shorter and fewer lymph nodes were dissected in the open surgery group than in the laparoscopy group (P ＜ 0.05). The time to flatus, fever duration, and hospital stay in stage ⅠB1 and ⅡA1 patients in the open surgery group were longer than in the laparoscopy group (P ＜ 0.05). The frequency of painkiller use in stage ⅡA1 patients in the open surgery group was greater than in the laparoscopy group (P ＜ 0.05). There was no statistical difference in the incidence of intraoperative and postoperative complications between the ⅠB1 and ⅡA1 groups (P＞ 0.05). The physical fitness and social function scores and the adverse effects were significantly different in the open surgery group from those in the laparoscopy group (P ＜ 0.05). Conclusion Laparoscopic radical hysterectomy and PLND for CSCC can reduce intraoperative bleeding volume, increase the number of lymph nodes dissected, shorten the fever duration and hospital stay, and increase the quality of life.关键词
子宫颈鳞状细胞癌/腹腔镜/广泛性子宫切除术/盆腔淋巴结清扫Key words
cervical squamous cell carcinoma/laparoscopy/radical hysterectomy/pelvic lymph node dissection分类
医药卫生引用本文复制引用
原昕,孟凡东..腹腔镜下广泛性子宫切除术治疗子宫颈鳞状细胞癌的临床疗效[J].中国医科大学学报,2019,48(1):48-52,5.基金项目
辽宁省教育厅高校重点实验室支持计划 (LS2010170) （LS2010170）
