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产油微藻基因组编辑技术研究进展

郝夏晖 黄凤洪 龚阳敏

中国油料作物学报2019,Vol.41Issue(1):144-150,7.
中国油料作物学报2019,Vol.41Issue(1):144-150,7.DOI:10.7505/j.issn.1007-9084.2019.01.019

产油微藻基因组编辑技术研究进展

Research progress in genome editing technologies in oleaginous microalgae

郝夏晖 1黄凤洪 1龚阳敏1

作者信息

  • 1. 中国农业科学院油料作物研究所/农业部油料作物生物学与遗传重点实验室, 湖北 武汉, 430062
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摘要

Abstract

Low biomass and lipid productivities of microalgae are main reasons for the difficulty in commercial production of microalgal oils. Newly established gene editing techniques, TALEN and CRISPR/Cas9, have great potential in analysis of key genes in lipid biosynthesis pathway and further genetic modification ofoil-producing algal strains. This review not only introduced TALEN and CRISPR/Cas9 techniques and their application in microalgal research, but also elaborated their importance in gene function study of oleaginous microalgae and construction of industrial strains.

关键词

微藻/基因组编辑/TALEN/CRISPR/Cas9/油脂

Key words

microalgae/genome editing/TALEN/CRISPR/Cas9/lipid

分类

生物科学

引用本文复制引用

郝夏晖,黄凤洪,龚阳敏..产油微藻基因组编辑技术研究进展[J].中国油料作物学报,2019,41(1):144-150,7.

基金项目

中国农业科学院科技创新工程项目 (CAAS-ASTIP-2013-OCRI) (CAAS-ASTIP-2013-OCRI)

中国油料作物学报

OA北大核心CSCDCSTPCD

1007-9084

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