中国药物经济学2019，Vol.14Issue(2)：50-52,73,4.DOI:10.12010/j.issn.1673-5846.2019.02.009
黄刺玫果提取物对小鼠急性酒精性氧化应激反应的影响
Effects of Rosa xanthina Lindl Fruit Extract on Acute Alcoholic Oxidative Stress Reaction Mice
摘要
Abstract
Objective To study the antioxidant effect of Rosa xanthina Lindl fruit extract on acute alcoholic oxidative stress reaction mice. Methods Mice were randomly divided into 5 groups: blank control group, model group, low, medium and high dose of Rose xanthina Lindl fruit extract groups. The model was established by intragastric administration of 50％ ethanol.Determined the contents of superoxide dismutase (SOD), reduced glutathione (GSH), malondialdehyde (MDA) and protein carbonyl in serum and liver tissue. Results The model of ethanol oxidation was successfully established. Compared with the model group, the differences of SOD, GSH, MDA and protein carbonyl in serum of medium-dose group and high-dose group had statistical significance (P＜0.05). Compared with the model group, the differences of SOD, GSH, MDA and protein carbonyl in liver tissue of medium-dose group and high-dose group had statistical significance (P＜0.05). Conclusion Rose xanthina Lindl fruit extract has antioxidant effect on acute alcoholic oxidative stress reaction in mice, which provides experimental basis for the development of functional food using Rose xanthina Lindl fruit.关键词
黄刺玫果/急性酒精/抗氧化Key words
Rosa xanthina Lindl fruit/Acute alcohol/Antioxidatio分类
医药卫生引用本文复制引用
薛润苗,张文琴,王美,王晓燕..黄刺玫果提取物对小鼠急性酒精性氧化应激反应的影响[J].中国药物经济学,2019,14(2):50-52,73,4.基金项目
山西省科技攻关项目(20150311022-1) （20150311022-1）
山西省重点研发计划项目(201803D31216) （201803D31216）
