中国医学创新2019，Vol.16Issue(1)：149-152,4.DOI:10.3969/j.issn.1674-4985.2019.01.040
神经节苷脂与普拉克索联合治疗血管性帕金森的临床效果评价
Clinical Efficacy of Ganglioside Combined with Pramipexole in Treatment of Vascular Parkinson
袁晓莉 1李裕民 1王博1
作者信息
- 1. 广东省农垦中心医院,广东 湛江 524002
- 折叠
摘要
Abstract
Objective:To investigate the clinical effect of Ganglioside combined with Pramipexole in treatment of vascular parkinson.Method:A total of 86 patients with vascular parkinson admitted to our hospital from January 2015 to January 2018 were selected.According to the odd and even number of admission numbers, they were divided into control group and observation group in proportion (1︰1), 43 cases in each group.The control group was treated with Dopazide, while observation group was treated with Ganglioside combined with Pramipexole.The UPDRS scores before and after treatment, therapeutic effects and adverse reactions of two groups were compared.Result:After 8 and 12 weeks of treatment, the UPDRS scores of two groups were lower than those of before treatment, and observation group were lower than those of control group, the difference were statistically significant (P<0.05).The total effective rate was 90.70％in observation group, which was higher than 72.09％in control group (P<0.05).The incidence of adverse reactions in observation group was 9.30％, which was lower than 25.58％in control group (P<0.05).Conclusion:Ganglioside combined with Pramipexole is effective in treatment of vascular parkinson, which can effectively improve the patients'condition, and the incidence of adverse reactions is low.It is worth of popularizing and applying.关键词
血管性帕金森/神经节苷脂/普拉克索/UPDRSKey words
Vascular parkinson/Ganglioside/Pramipexole/UPDRS引用本文复制引用
袁晓莉,李裕民,王博..神经节苷脂与普拉克索联合治疗血管性帕金森的临床效果评价[J].中国医学创新,2019,16(1):149-152,4.
