中国医学创新2019，Vol.16Issue(2)：164-167,4.DOI:10.3969/j.issn.1674-4985.2019.02.042
膜性肾病诊断与治疗新进展
Membranous Nephropathy:A Review on the Diagnosis and Treatment
摘要
Abstract
Membranous nephropathy (MN) is a unique glomerulonephritis, it is the most common cause of nondiabetic idiopathic nephrotic syndrome in adults.The etiology of approximately 80％ MN cases is idiopathic, and 20％ is associated with other systemic diseases or exposure.Anti phospholipase A2 receptor antibody is associated with idiopathic MN.This finding may contribute to the diagnosis and prognosis of MN.Current treatment for MN is mainly the best supportive treatment, including the use of angiotensin converting enzyme inhibitors/angiotensin Ⅱ receptor blockers, lipid-lowering drugs and good blood pressure control.Immunosuppressive agents are used in patients with refractory proteinuria or nephrotic syndrome with associated complications.Available evidence supports the combination of steroids and alkylating agents.This article reviews the latest research progress in the diagnosis and treatment of MN.关键词
膜性肾病/磷脂酶A2受体抗体/诊断/预后/治疗Key words
Membranous nephropathy/Phospholipase A2 receptor antibody/Diagnosis/Prognosis/Treatment引用本文复制引用
刘建芳,齐凯敏,刘光珍..膜性肾病诊断与治疗新进展[J].中国医学创新,2019,16(2):164-167,4.基金项目
山西省重点研发计划重点项目计划(201603D3113023) （201603D3113023）
山西省重点研发计划(指南)项目(201703D421024) （指南）
