中国医学创新2019，Vol.16Issue(3)：20-24,5.DOI:10.3969/j.issn.1674-4985.2019.03.005
加巴喷丁在全膝关节置换术后镇痛效果中的前瞻性研究
A Prospective Study of Analgesic Effect of Gabapentin after Total Knee Arthroplasty
王帆 1贺智榆 2陈孝均2
作者信息
- 1. 四川省泸州市纳溪区中医医院, 四川 泸州 646300
- 2. 西南医科大学附属中医医院
- 折叠
摘要
Abstract
Objective:To investigate the analgesic effect of Gabapentin in the evaluation of pain management after total knee arthroplasty (TKA).Method:Randomized, double-blind, placebo controlled from October 2016 and February 2018, 80 patients underwent unilateral TKA were randomly divided into two groups, 40 cases each in each group.After surgery, Gabapentin group took Gabapentin Capsules regularly and placebo group took Lactose Placebo Capsules, the analgesic effects of two groups were compared.Result:Gabapentin Capsule, as an assistant analgesic drug in multi-mode and multi-link pain management, can effectively improve the pain in 48 h after surgery.At the same time, it significantly improved the functional recovery in the early (7 d) after knee surgery, and there was no obvious drug adverse reaction.However, there was no statistical significant difference in the recovery of knee joint function between two groups at the six-month follow-up (P＞0.05).Conclusion:Gabapentin Capsule has a definite analgesic effect. It can effectively relieve pain after total knee arthroplasty, promote early joint activity, shorten hospitalization time, and do not increase adverse drug reactions.It is an ideal analgesic drug.关键词
加巴喷丁胶囊/全膝关节置换术/镇痛Key words
Gabapentin Capsule/Total knee arthroplasty/Analgesia引用本文复制引用
王帆,贺智榆,陈孝均..加巴喷丁在全膝关节置换术后镇痛效果中的前瞻性研究[J].中国医学创新,2019,16(3):20-24,5.
