摘要
Abstract
Objective:To investigate the effect on stress response, immune function and gastrointestinal function of laparoscopic cholecystectomy (LC) in the treatment of acute calculous cholecystitis (ACC). Method:A total of 78 patients with ACC from January 2016 to April 2018 were enrolled in the study.They were randomly divided into two groups, the control group (39 cases) treated with traditional open cholecystectomy (OC) and the observation group (39 cases) treated with LC.Endothelin (ET), leukocyte (WBC), high-sensitivity C-reactive protein (hs-CRP), gastrointestinal function recovery time, T-cell factors CD3+, CD4+ and CD8+ were compared between two groups before and after operation.Result:1 d after surgery, ET, WBC, hs-CRP increased in two groups, the stress indexes in the observation group were better than those in the control group (P＜0.05). 1 d after surgery, CD3+, CD4+, CD8+ decreased in two groups, and the immune indexes in the observation group were better (P＜0.05).Compared with the control group, the gastrointestinal function in the observation group recovered faster, the difference was significant (P＜0.05).Conclusion:Laparoscopic cholecystectomy in the treatment of acute calculous cholecystitis has a prominent clinical efficacy, which have a positive impact on stress response, immune function, gastrointestinal function, and is suitable for clinical promotion and application.关键词
腹腔镜胆囊切除术/急性结石性胆囊炎/应激反应/免疫功能/胃肠功能Key words
Laparoscopic cholecystectomy/Acute calculous cholecystitis/Stress response/Immune function/Gastrointestinal function
