中国药业2018，Vol.27Issue(21)：55-57,3.DOI:10.3969/j.issn.1006-4931.2018.21.017
布拉氏酵母菌佐治小儿厌食症对微量元素与脑肠肽水平的影响
Clinical Effect of Saccharomyces Boulardii in the Adjuvant Treatment of Infantile Anorexia and Its Effect on Trace Elements and Braingut Peptide Level
摘要
Abstract
Objective To investigate the clinical effect of Saccharomyces boulardii (Bioflor) in the adjuvant treatment of children patients with infantile anorexia and its effect on trace elements and braingut peptide level. Methods Totally 97 children patients with infantile anorexia admitted to Tangshan Fengnan District Hospital from June 2016 to October 2017 were selected and divided into the observation group (48 cases) and the control group (49 cases) by the random number table method. The children in the two groups were corrected bad eating habits. The control group was given Zinc Gluconate Oral Solution, on this basis, the observation group was given Saccharomyces boulardii Sachets. The two groups were treated for 8 weeks. Results The total effective rate of the observation group was91. 67％, which was significantly higher than 75. 51％ of the control group (P ＜ 0. 05). The levels of serum zinc, iron, gastrin (GAS), motilin (MTL), and β-endorphin (β-EP) in the two groups were increased, and the increase in the observation group was more significant than that in the control group (P ＜ 0. 05). No significant adverse reaction was found in the two groups during treatment. Conclusion Saccharomyces boulardii is effective and safe in the adjuvant treatment of children patients with infantile anorexia, its mechanism may be through regulating the level of trace elements in the body and the secretion and release of GAS, MTL, β-EP and other brain-gut peptide to promote appetite.关键词
布拉氏酵母菌/葡萄糖酸锌/小儿厌食症/临床疗效/作用机制/微量元素/脑肠肽Key words
Saccharomyces boulardii/Zinc Gluconate Oral Solution/infantile anorexia/clinical effect/mechanism/trace element/braingut peptide分类
医药卫生引用本文复制引用
高翠云,丁红炜,郭战..布拉氏酵母菌佐治小儿厌食症对微量元素与脑肠肽水平的影响[J].中国药业,2018,27(21):55-57,3.基金项目
河北省科技计划项目[162777264] （）
