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血塞通对脑梗死并脑心综合征患者心肌损伤指标和左心室功能的影响

刘德浪 余洪 刘卫花

中国药业2018,Vol.27Issue(21):67-69,3.
中国药业2018,Vol.27Issue(21):67-69,3.DOI:10.3969/j.issn.1006-4931.2018.21.021

血塞通对脑梗死并脑心综合征患者心肌损伤指标和左心室功能的影响

Effect of Xuesaitong on Myocardial Injury Indexes and Left Ventricular Function in Patients with Cerebral Infarction Complicated with Cerebrocardiac Syndrome

刘德浪 1余洪 1刘卫花1

作者信息

  • 1. 海南省中医院, 海南 海口 510203
  • 折叠

摘要

Abstract

Objective To investigate the effect of Xuesaitong on myocardial injury indexes and the left ventricular function in patients with cerebral infarction complicated with cerebrocardiac syndrome. Methods Totally 60 patients with cerebral infarction complicated with cerebrocardiac syndrome admitted to our hospital from June 2014 to June 2017 were selected and randomly divided into the control group and the treatment group by the random number table method, 30 cases in each group. The control group was given conventional treatment, on the basis, the treatment group was additionally treated with Xuesaitong Injection. Results The total effective rate of the treatment group was 93. 33%, which was significantly higher than 73. 33% of the control group (P < 0. 05). After treatment, the National Institutes of Health Stroke Scale (NIHSS) scores, levels of creatine kinase-MB (CK-MB), troponin I (TnI), C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in the two groups were significantly decreased (P < 0. 05), and those in the treatment group were significantly lower than those in the control group (P < 0. 05). After treatment, the arrhythmia rate and ST-T change rate in the treatment group were significantly lower than those in the control group (P < 0. 05). There were no obvious adverse reactions in the two groups. Conclusion Xuesaitong is effective in the treatment of cerebral infarction complicated with cerebrocardiac syndrome, it can obviously relieve the abnormal symptoms of electrocardiogram, the myocardial injury and inflammatory reactions, which is good for the recovery of neurological function.

关键词

脑梗死/脑心综合征/血塞通注射液/心肌损伤/心电图/临床疗效

Key words

cerebral infarction/cerebrocardiac syndrome/Xuesaitong Injection/myocardial injury/electrocardiogram/clinical effect

分类

医药卫生

引用本文复制引用

刘德浪,余洪,刘卫花..血塞通对脑梗死并脑心综合征患者心肌损伤指标和左心室功能的影响[J].中国药业,2018,27(21):67-69,3.

中国药业

OACSTPCD

1006-4931

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