中国医院用药评价与分析2019，Vol.19Issue(1)：29-30,33,3.DOI:10.14009/j.issn.1672-2124.2019.01.010
依达拉奉注射液用于急性脑梗死的疗效观察
Observation on Efficacy of Edaravone Injection in Treatment of Acute Cerebral Infarction
李竹莲 1曾冬兰 2刘爱军2
作者信息
- 1. 江西省新干县人民医院药剂科, 江西 新干 331300
- 2. 江西省新干县人民医院心脑血管科, 江西 新干 331300
- 折叠
摘要
Abstract
OBJECTIVE:To probe into the efficacy of edaravone injection in treatment of acute cerebral infarction (ACI). METHODS:66 patients with ACI admitted into Jiangxi Xin'gan County People's Hospital from Jun. 2017 to Jul. 2018 were selected and divided into observation group and control group via random number table, with 33 cases in each. The control group was given conventional therapy, while the observation group was given edaravone injection based on the control group. Differences in clinical efficacy, interleukin-6 (IL-6), interleukin-13 (IL-13), endothelin-1 (ET-1), malondialdehyde (MDA) and superoxide dismutase (SOD) levels between two groups were compared. RESULTS:The total effective rate of observation group was 87.88％ (29/33), which was significantly higher than that of the control group (63.64％, 21/33), with statistically significant difference (P＜0.05); after treatment, the IL-6, IL-13, ET-1, MDA and SOD levels of observation group were significantly better than those of control group, with statistically significant differences (P＜0.05). CONCLUSIONS:The efficacy of edaravone injection in treatment of ACI is remarkable.关键词
依达拉奉注射液/急性脑梗死/临床效果Key words
Edaravone injection/Acute cerebral infarction/Clinical efficacy分类
医药卫生引用本文复制引用
李竹莲,曾冬兰,刘爱军..依达拉奉注射液用于急性脑梗死的疗效观察[J].中国医院用药评价与分析,2019,19(1):29-30,33,3.
