中国医院用药评价与分析2019，Vol.19Issue(2)：200-201,204,3.DOI:10.14009/j.issn.1672-2124.2019.02.026
布地奈德联合特布他林治疗小儿支气管哮喘的疗效及安全性
Efficacy and Safety of Budesonide Combined with Terbutaline in Treatment of Children with Bronchial Asthma
张玉娥 1龚宝先1
作者信息
- 1. 湖北省谷城县人民医院儿科, 湖北 谷城 441700
- 折叠
摘要
Abstract
OBJECTIVE: To probe into the efficacy and safety of budesonide combined with terbutaline in treatment of children with bronchial asthma. METHODS: 84 children with bronchial asthma admitted into Hubei Gucheng County People's Hospital from Feb. 2016 to Feb. 2018 were extracted to be randomly divided into observation group and control group, with 42 cases in each. The observation group was treated with inhalation budesonide suspension combined with terbutaline sulfate nebulized solution, and the control group only received budesonide suspension for inhalation. The clinical efficacy, relief time of clinical symptoms, incidence of adverse drug reactions and recurrence of two groups were compared. RESULTS: The total effective rate of the observation group was 92.86％ (39/42), significantly higher than that of the control group (80.95％, 34/42), the difference was statistically significant (P＜0.05). The relief time of wheezing, coughing and chest distress in the observation group was significantly shorter than that in the control group, with statistically significant differences (P＜0.05). The incidence of adverse drug reactions and recurrence in the observation group were 7.14％ (3/42) and 4.76％ (2/42), significantly lower than those in the control group [21.43％ (9/42) and 16.67％ (7/42) ], the difference was statistically significant (P＜0.05). CONCLUSIONS: The efficacy of budesonide combined with terbutaline in treatment of children with bronchial asthma is significant, which can effectively alleviate the clinical symptoms, reduce the incidence of adverse drug reactions and recurrence, and improve the prognosis.关键词
小儿支气管哮喘/布地奈德混悬液/硫酸特布他林雾化液Key words
Children with bronchial asthma/Budesonide suspension for inhalation/Terbutaline sulfate nebulized solution分类
医药卫生引用本文复制引用
张玉娥,龚宝先..布地奈德联合特布他林治疗小儿支气管哮喘的疗效及安全性[J].中国医院用药评价与分析,2019,19(2):200-201,204,3.
