中国真菌学杂志2018，Vol.13Issue(6)：367-370,4.
白念珠菌White-Gray-Opaque表型转换系统的研究进展
Research progress of White-Gray-Opaque phenotypic switching system in Candida albicans
摘要
Abstract
Candida albicans is a common opportunistic fungal pathogen of humans.An important biological feature of this fungus is its phenotypic transition, and diverse morphological phenotypes play distinct roles in host adaptation, infection and virulence during different life stages.White-Gray-Opaque phenotypic switching system is a novel phenotypic transition in Candida albicans.In this review, research achievements about this phenotypic transition were mentioned, including the traits of White-Gray-Opaque phenotype, the key regulatory factors and the interaction with hosts.In a nutshell, understanding about the molecular mechanisms of this phenotypic transition in Candida albicans might be beneficial to the discovery of novel infection treatment strategies.关键词
白念珠菌/表型转换/调节因子/毒力Key words
Candida albicans/phenotypic transitions/regulatory factors/virulence分类
医药卫生引用本文复制引用
王钰婷,刘锦燕,赵悦,孟玲宁,项明洁..白念珠菌White-Gray-Opaque表型转换系统的研究进展[J].中国真菌学杂志,2018,13(6):367-370,4.基金项目
上海市卫计委课题 (201740069) （201740069）
上海市黄浦区卫计委课题 (HKM201702) （HKM201702）
