中华神经创伤外科电子杂志2019，Vol.5Issue(1)：20-24,5.DOI:10.3877/cma.j.issn.2095-9141.2019.01.005
神经内镜与神经导航辅助显微镜下经鼻蝶入路切除垂体瘤的疗效比较
Neuroendoscopic and neuronavigation-assisted microscopy for the treatment of pituitary tumors via transsphenoidal approach
王宁 1刘立军 1陈妮娜1
作者信息
- 1. 湖北医药学院附属襄阳市第一人民医院神经外科,441000 襄阳
- 折叠
摘要
Abstract
Objective To compare the clinical efficacy of neuroendoscopy and neuronavigation assisted microscopy in the treatment of pituitary tumors by transnasal transsphenoidal approach.Methods One hundred and sixty patients with pituitary adenoma admitted to Xiangyang First People 's Hospital Affiliated to Hubei Medical College from January 2016 to July 2018 were selected. The patients were randomly divided into neural endoscopic group (neural endoscopic nasal adjustment approach resection of pituitary adenoma) and neural navigation group (neural navigation AIDS microscope nasal adjustment approach resection of pituitary adenoma), 80 patients in each group. Comparing two groups of patients before and after the treatment of growth hormone, prolactin (PRL), growth hormone (GH) and adrenocorticotropic hormone (ACTH) content difference, comparing two groups of patients with operation indicators, clinical curative effect and complications of statistical difference. Results The operation time in the neuroendoscopic group was shorter than that in the neuronavigation group, the intraoperative blood loss in the neuroendoscopic group was less than that in the neuronavigation group, and the postoperative hospitalization time in the neuroendoscopic group was shorter than that in the neuronavigation group. After treatment, PRL, GH and ACTH contents in patients in the neuronavigation group were significantly higher than those in the neuroendoscopy group. The effective rate of patients in the neuroendoscopic group (92.50％) was higher than that in the neuronavigation group (81.25％). The incidence of diabetes insipidus, visual impairment and nasal bleeding in the neuronavigation group was significantly higher than that in the neuroendoscopy group (P <0.05). Conclusion Compared with neuronavigation-assisted microscopy for the resection of pituitary tumor through nasal transsphenoidal approach, neuroendoscopy has better clinical efficacy, fewer complications and better recovery of pituitary function.关键词
神经内镜/神经导航辅助显微镜/鼻蝶入路/垂体瘤Key words
Neuroendoscopy/Neuronavigation-assisted microscopy/Nasal approach/Pituitary tumor引用本文复制引用
王宁,刘立军,陈妮娜..神经内镜与神经导航辅助显微镜下经鼻蝶入路切除垂体瘤的疗效比较[J].中华神经创伤外科电子杂志,2019,5(1):20-24,5.
