中国现代医生2019，Vol.57Issue(10)：90-94,5.
病程对老年2型糖尿病患者认知功能及相关危险因素的影响
Effect of disease course on the cognitive function and related risk factors in the elderly patients with type 2 diabetes
摘要
Abstract
Objective To investigate the effects of disease course on cognitive function and related risk factors in elderly patients with type 2 diabetes. Methods A total of 193 patients with type 2 diabetes were selected and divided into 4 groups according to the course of disease, the new diagnosis group, the group of the course of disease within 1 year, the group of the course of disease between 1-5 years and the group of the course of disease over 5 years. The general clinical features, biochemical indicators and neuropsychological test scores among the groups were compared.Results Age (P=0.024), treatment methods (P<0.001), and total cholesterol (P=0.037) were significantly different among the groups of different courses of disease. Logistic regression analysis using cognitive dysfunction as a dependent variable revealed that the course of diabetes (OR=1.205, 95％CI=1.128-1.286) and medical treatment (OR=2.931, 95％CI=1.067-8.053) was associated with cognitive dysfunction. Conclusion There is a cognitive dysfunction in the elderly patients with type 2 diabetes, and the course of diabetes is an important risk factor.关键词
2型糖尿病/认知功能/阿尔茨海默病/危险因素Key words
Type 2 diabetes/Cognitive function/Alzheimer's disease/Risk factors分类
医药卫生引用本文复制引用
陈浙丽,倪琳,沈鑫华,雷礼磊,那万秋,潘新根,陈科,何卫亮..病程对老年2型糖尿病患者认知功能及相关危险因素的影响[J].中国现代医生,2019,57(10):90-94,5.基金项目
浙江省湖州市科技局公益性技术应用研究(一般)项目(2014GY17) （一般）
浙江省公益技术研究计划/社会发展项目(LGF18H250001) （LGF18H250001）
