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超声联合酶法提取玫瑰花总黄酮工艺条件优化

何效平 王柏强 曾芝兰 罗飞 罗巧林

中国现代中药2019,Vol.21Issue(1):99-103,5.
中国现代中药2019,Vol.21Issue(1):99-103,5.DOI:10.13313/j.issn.1673-4890.20171017001

超声联合酶法提取玫瑰花总黄酮工艺条件优化

Optimization on Extraction Technology of Flavonoids from Rosa rugosa by Ultrasound Combined with Cellulose Enzyme

何效平 1王柏强 1曾芝兰 1罗飞 1罗巧林1

作者信息

  • 1. 川北医学院附属医院 药剂科, 四川 南充 637000
  • 折叠

摘要

Abstract

Objective: The extraction process of flavonoids in Rosa rugosa by ultrasound combined with cellulose enzyme was optimized. Methods: The extraction rate of flavonoids was used as index. Based on the effects of some factors such as enzymatic temperature, enzyme mass concentration, ratio to solid, the concentration of ethanol, ultrasonic time and ultrasonic temperature, orthogonal design was applied to decide the best extraction process. Results: The optimal extraction technology was as follows: ratio to solid was 1: 25, enzymatic temperature was 50 ℃, enzyme mass concentration was 0. 4%, ultrasonic time was 30 min. Conclusion: The optimized process is reasonable and feasible, which can enhance extract-efficiency and is energy-saving. It provides reference for industrial production.

关键词

玫瑰花/超声波/纤维素酶/总黄酮

Key words

Rosa rugosa/ultrasound/cellulose enzyme/flavonoids

分类

医药卫生

引用本文复制引用

何效平,王柏强,曾芝兰,罗飞,罗巧林..超声联合酶法提取玫瑰花总黄酮工艺条件优化[J].中国现代中药,2019,21(1):99-103,5.

中国现代中药

OACSTPCD

1673-4890

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