国际医药卫生导报2019，Vol.25Issue(11)：1730-1733,4.DOI:10.3760/cma.j.issn.1007-1245.2019.11.015
ICU危重症患者呼吸机相关感染的病原菌分布及耐药性分析
Distribution and drug resistance of pathogens causing ventilator-associated infections in critically ill patients in ICU
摘要
Abstract
Objective To investigate the distribution and drug resistance of pathogens isolated from the critical patients with ventilator-associated infections in ICU from our hospital.Methods 561 critically ill patients treated by mechanical ventilation from January,2016 to December,2017 in the ICU of our hospital were selected.65 sputum specimens from the patients with ventilator related infection were collected,and the bacteria were cultured and isolated.The bacterial identification and drug sensitivity test were carried out by VITEK 2-Compact automatic bacterial identification instrument,and the results were statistically analyzed by WHONET5.6.Results Among the 65 patients with ventilator-associated infection,101 strains of pathogenic bacteria were cultured.There were 71 strains of negative bacteria,accounting for 70.30％;9 strains of positive bacteria,accounting for 8.91％;and 21 strains of fungi,accounting for 20.79％.Among the gram-negative bacilli,the top three pathogenic bacteria were 22 strains of acinetobacter bauman,accounting for 21.78％;20 strains of pseudomonas aeruginosa,accounting for 19.80％;and 12 strains of klebsiella pneumoniae,accounting for 11.89％.The 9 strains of Gram-positive bacteria were staphylococcus aureus.The drug sensitivity results showed that the proportion of carbapenem resistant acinetobacter bauman (CRABA) was 95.2％,the proportion of carbapenem resistant pseudomonas aeruginosa (CRPAE) was 28.6％,and the proportion of methicillin resistant staphylococcus aureus (MRSA) was 100.0％.Conclusion The pathogenic bacteria associated with ventilator related infection in critically ill patients in the ICU in our hospital are mainly Gram-negative bacteria;the proportions of MRSA,CRABA,and CRPAE are very high,which brings severe test to clinical treatment.It is necessary to take corresponding countermeasures to control drug resistant bacteria.关键词
ICU危重症/呼吸机相关感染/病原菌/耐药性Key words
Critically ill patients in ICU/Ventilator associated infection/Pathogens/Drug resistance引用本文复制引用
钟瑞雪,谢伟贤,周少雄,黄泽棋,江丽嫦,邹林..ICU危重症患者呼吸机相关感染的病原菌分布及耐药性分析[J].国际医药卫生导报,2019,25(11):1730-1733,4.基金项目
佛山市医学重点专科培育项目(Fspy3-2015022)Training Project of Key Medical Subjects in Foshan (Fspy3-2015022) （Fspy3-2015022）
