河北医学2019，Vol.25Issue(6)：894-898,5.DOI:10.3969/j.issn.1006-6233.2019.06.004
三种修复金属材料对口腔修复患者牙周组织 龈沟液中炎症因子水平的影响
Effects of Three Kinds of Metal Repair Materials on the Levels of Inflammatory Factors in Periodontal Tissues and Gingival Crevicular Fluid of Patients with Oral Prosthetics
摘要
Abstract
Objective: To explore the effects of three kinds of metal repair materials on the levels of inflammatory factors in periodontal tissues and gingival crevicular fluid of patients with oral prosthetics. Methods: A total of 213 patients with anterior porcelain fused to metal (PFM) full crown repair were selected. According to the three PFM repair materials, they were divided into nichrome PFM group (group A, n = 71) and cobalt -chromium alloy PFM group (group B, n= 71) and gold deposition PFM group ( group C, n= 71) . And they were given 6 months of effective follow-up after oral prosthesis. The periodontal tissues, gingival crevicular fluid (GCF), gingival crevicular depth (GCD) , gingival index (GI), gingival probing depth (GCD) , gingival index (GI), receptor activator of NF-kB ligand (RANKL), osteoprotegerin (OPG) and RANKL/OPG ratio were detected in the three groups before repair and after 6 months of repair. Results : After 6 months of repair, the gingival crevicular fluid (GCF) in group A was significantly increased (P<0.05) , and the gingival crevicular depth (GCD) was significantly prolonged (P<0.05) , and the gingival index (GI) was increased (P<0.05) , and there were no significant differences between group A and group B at different time points (P>0.05) , and the above indexes in groups B and C were significantly lower than those in group A (P<0.05). After 6 months of repair, the levels of interleukin -1β(IL-1β), interleukin-6 (IL-6) and matrix metalloproteinase-2 (MMP-2) in periodontal tissues and gingival crevicular fluid were increased significantly in the three groups (P<0.05) , and the receptor activator of NF - kB ligand (RANKL), osteoprotegerin (OPG) and RANKL/OPG ratio were significantly increased (P<0.05) , and the changes in group A were significantly greater than those in group B and C (P<0.05), and there were no significant differences between the two groups (P>0.05). Conclusions: Cobalt-chromium alloy and gold precipitation PFM have less irritation to periodontal tissues than nickel-chromium alloy PFM. Inflammatory reaction in gingival crevicular fluid and bone absorption in alveolar bone of patients are lighter than nickel-chromium alloy PFM, which is suitable for clinical promotion.关键词
口腔修复/修复金属材料/牙周组织/龈沟液Key words
Oral prosthetics/Metal repair materials/Periodontal tissues/Gingival crevicular fluid引用本文复制引用
赵恒越1,何文娟2..三种修复金属材料对口腔修复患者牙周组织 龈沟液中炎症因子水平的影响[J].河北医学,2019,25(6):894-898,5.基金项目
湖北省卫生厅科研项目,(编号:1409254) （编号:1409254）
