分子影像学杂志2019,Vol.42Issue(2):249-252,4.
不同胎龄早产儿实足24月龄神经心理发育状况分析
Neurodevelopment of premature infants with different gestational ages at 24 months old
杨静仪 1黄赛君 1何小颖 1颜玉 1廖燕薇 1吴翠玲1
作者信息
- 1. 佛山市妇幼保健院儿童保健科,广东 ?佛山 ?528000
- 折叠
摘要
Abstract
ObjectiveTo investigate the neurodevelopment of premature infants with different gestational ages at 24 months old.MethodsA total of 159 premature infants of 24 months old were recruited. The cases were divided into low-risk group (34 weeks≤GA<37 weeks, n=97), intermediate-risk group (32 weeks≤GA<34 weeks, n=36) and high-risk (GA<32 weeks, n=26) group. Neurodevelopment was evaluated by Neuropsychological development scale for children aged 0-6 years at the corrected age of 12 months and at the actual age of 24 months. The severe neonatal complications in relation to neurodevelopment were analyzed.ResultsSevere neonatal complications, such as neonatal hyperbilirubinemia, neonatal asphyxia, intracranial hemorrhage and neonatal respiratory distress syndrome, were significantly increased in the high-risk group (P<0.05). Development quotients (DQ) of each area in three groups at the corrected 12 months old reached a normal level . No significant differences of average DQ were detected among the three groups (P>0.05). The multiple area DQ of the 24 months old infants in the high-risk group were at low levels, except for the motor area DQ. The motor and cognitive area DQ of the intermediate-risk group at the age of 24 months reached the normal level, but the other areas DQ were still lower than the normal level. The average DQ of 3 groups at 24 months of age (F=2.14) were lower than that of the normal level, and no significant differences were detected among 3 groups (P>0.05).ConclusionPremature infants with different gestational ages has a good catch-up growth in the neurodevelopment at the corrected age of 12 months. However, among the neurodevelopment assessment of the 24 months old infants, only motor development in the high-risk group and the motor and cognitive development in the low- and intermediate-risk groups can catch up to the normal level.关键词
早产儿/ 胎龄/ 神经心理发育/ Key words
preterm infants/ gestational age/ neuropsychological development/ 引用本文复制引用
杨静仪,黄赛君,何小颖,颜玉,廖燕薇,吴翠玲..不同胎龄早产儿实足24月龄神经心理发育状况分析[J].分子影像学杂志,2019,42(2):249-252,4.