昆明医科大学学报2018，Vol.39Issue(3)：90-94,5.
不同手术对胃肠间质瘤的疗效及患者围术期指标、预后的影响
Efficacy of Different Surgeries for Gastrointestinal Stromal Tumors and their Effects on Perioperative Indexes and Prognosis
摘要
Abstract
Objective To explore the efficacy of different surgeries for gastrointestinal stromal tumors (GIST) and their effects on perioperative indexesand prognosis. Methods 60 cases of GIST patients admitted in our hospital from October 2006 to November 2016 were selected and were divided into the study group (n =35, given the laparoscopic surgery) and the control group (n =25, given the laparotomy). The perioperative indexes, gastrointestinal function before and after operation [ (gastrin (GAS), motilin (MTL), vasoactive intestinal peptide (VIP) ], postoperative recurrence risk grade and complications were recorded in the two groups. Results There was no significant difference between the two groups in the operation time (P＞0.05), and the intraoperative blood loss volume and postoperative 3 d pain score in the study group were lower than those in the control group, and the postoperative exhaust time, eating time and hospital stay were shorter than those in the control group (P＜0.05). The levels of plasma GAS, MTL and VIP in the study group were higher than those in the control group after operation (P＜0.05). There was no significant difference in the postoperative recurrence risk grade and the incidence rate of complications between the two groups (P＞0.05). Conclusions Compared with the conventional laparotomy, laparoscopic surgery has better efficacy for GIST and has advantages of small trauma, mild pain and fast postoperative gastrointestinal function recovery, and it will not increase the risk of long-term recurrence and complications, therefore it has a good application prospect.关键词
腹腔镜/开腹手术/胃肠间质瘤/围术期指标/预后Key words
Laparoscopy/Laparotomy/Gastrointestinal stromal tumors/Perioperative indexes/Prognosis分类
医药卫生引用本文复制引用
严海,胡清林,鄢传经,黄丹,黄昊..不同手术对胃肠间质瘤的疗效及患者围术期指标、预后的影响[J].昆明医科大学学报,2018,39(3):90-94,5.基金项目
四川省科技厅科技支撑计划(2013SZ156823) （2013SZ156823）
