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血液系统疾病相关肺高血压的流行病学与发病机制

冯友繁 张启科 曹云山 魏小芳 彭文辉

兰州大学学报(医学版)2018,Vol.44Issue(5):16-20,5.
兰州大学学报(医学版)2018,Vol.44Issue(5):16-20,5.DOI:10.13885/j.issn.1000-2812.2018.05.003

血液系统疾病相关肺高血压的流行病学与发病机制

Epidemiology and pathogenesis of pulmonary hypertension associated with haematological diseases

冯友繁 1张启科 1曹云山 2魏小芳 1彭文辉3

作者信息

  • 1. 甘肃省人民医院 血液科, 甘肃 兰州 730000
  • 2. 甘肃省人民医院 心内二科, 甘肃 兰州 730000
  • 3. 同济大学附属第十人民医院 心内科, 上海 200072
  • 折叠

摘要

Abstract

Pulmonary hypertension (PH) refers to high blood pressure within the pulmonary circulation, which is a kind of malignant pulmonary vascular disease with or without small pulmonary artery lesions, often causes right heart failure and even death. PH is closely related to a blood disease, but is not recognized in time by a hematologist. Reviewed in this study were blood diseases that might cause PH, such as hemolytic anemia, myeloproliferative diseases, plasma cell disease and treatment-related PH. Possible pathogenesis was also described, aiming at improving the hematologist's understanding of PH.

关键词

肺高血压/溶血性贫血/骨髓增殖性疾病/达沙替尼/脾切除/骨髓移植

Key words

pulmonary hypertension/hemolytic anemia/myeloproliferative diseases/dasatinib/splenectomy/bone marrow transplantation

分类

医药卫生

引用本文复制引用

冯友繁,张启科,曹云山,魏小芳,彭文辉..血液系统疾病相关肺高血压的流行病学与发病机制[J].兰州大学学报(医学版),2018,44(5):16-20,5.

基金项目

国家自然科学基金项目(81670230) (81670230)

兰州大学学报(医学版)

OACSTPCD

2097-681X

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