兰州大学学报（医学版）2018，Vol.44Issue(5)：67-71,5.DOI:10.13885/j.issn.1000-2812.2018.05.013
冻融胚胎移植周期添加小剂量人绒毛膜促性腺激素对妊娠结局影响的临床研究
Clinical study of the effect on pregnancy outcome of adding small dose of human chorionic gonadotropin in the frozen-thawed embryo transfer cycle
摘要
Abstract
Objective To investigate into the impact of endometrium preparation with adding small doses of human chorionic gonadotropin (hCG) in frozen-thawed embryos transfer (FET) cycle on clinical outcomes.Methods A retrospective analysis of FET cycle of 156 cases. Patients were divided into two groups, hCG group and the control group, according to the endometrial preparation program. We compared their embryo implantation rate, clinical pregnancy rate as well as endometrial blood flow, thickness, type, etc. Results Compared to the control group, the clinical pregnancy rate, embryo transfer rate, type I rate of endometrial blood flow, endometrial thickness on hCG trigger and transfer day, resistance index (RI) of basal artery blood flowand radiation artery flow were better than the control group, and the difference was statistically significant (P ＜ 0.05) . However, the abortion rate, ectopic pregnancy rate, biochemical pregnancy rate, time averaged maximum velocity, time averaged maximum velocity (TAMAX) of basal artery or radiate artery, systolic/diastolic ratio (S/D) and pulsatility index (PI) of basilar artery, S/D and PI of radiation artery showed no statistical significance (P＞ 0.05) . Conclusion The addition of a small dose of hCG during FET cycles can improve the endometrial blood flow of patients, presenting a feasible method to promote embryo implantation and improve the clinical pregnancy rate.关键词
冻融胚胎移植/人绒毛膜促性腺激素/子宫内膜容受性/子宫内膜血流Key words
frozen-thawed embryo transfer/human chorionic gonadotropin/endometrial receptivity/endometrial blood flow分类
医药卫生引用本文复制引用
贾学玲,高明霞,苟文婕,罗兴春,刘琨,刘龙会,潘从新..冻融胚胎移植周期添加小剂量人绒毛膜促性腺激素对妊娠结局影响的临床研究[J].兰州大学学报（医学版）,2018,44(5):67-71,5.基金项目
甘肃省卫生行业项目(GSWSKY-2015-47) （GSWSKY-2015-47）
