临床肝胆病杂志2018，Vol.34Issue(1)：181-183,3.DOI:10.3969/j.issn.1001-5256.2018.01.039
Notch信号通路与肝纤维化发生发展的关系
Relationship between the Notch signaling pathway and the development and progression of liver fibrosis
摘要
Abstract
The Notch signaling pathway mainly includes Notch receptors and ligands, transcription factors, and DNA binding proteins. It decides the way of cell proliferation, differentiation, and apoptosis. Recent studies have shown that the Notch signaling pathway plays an important role in the development and progression of liver fibrosis, and blocking or activating the Notch signaling pathway can influence the progression of liver fibrosis. This article reviews the research advances in the composition of the Notch signaling pathway, the mechanism by which it is activated, and its association with liver fibrosis.关键词
肝硬化/受体,Notch/信号传导/综述Key words
liver cirrhosis/receptors, Notch/signal transduction/review分类
医药卫生引用本文复制引用
张旭,刘平,慕永平..Notch信号通路与肝纤维化发生发展的关系[J].临床肝胆病杂志,2018,34(1):181-183,3.基金项目
国家自然科学基金面上项目(81173223,81573948) （81173223,81573948）
